The Kambo is the secretion of a frog, Phyollomedusa Bicolor. After having procured some small superficial wounds on the arms or legs of the person to be treated, the secretion of the frog is applied to get into the blood stream . The Kambo frog secretion contains peptides substances such as dermorphin and deltorphin that have analgesic properties enhancing the immune system, causing the destruction of pathogenic microorganisms through the production of antibodies as a reaction to the venom. The purgative effect also acts as a liver detoxification process, usually through the expulsion of bitter bile through vomiting and bowel movements. The effects last about fifteen minutes, and  within a half hour after the end of the treatment, the person is ready to return to his normal activities. The application of Kambo presented great benefits in the treatment of people with a low immune system, pain and inflammation in general, fatigue, tendinitis, migraine, asthma, allergies, ulcers, diabetes, constipation, high blood pressure and arterial circulatory, high cholesterol , cirrhosis, stress, menstrual irregularities, decreased libido, depression, panic attack and drug addiction. The kambo is to be avoided by people who have or have had cardiovascular problems, people suffering from high blood pressure (hypertension or hypotension) and who take medication for this condition, people suffering from severe respiratory disease, women who are pregnant or breastfeeding.